Biographie

Plusieurs fois lauréat du Prix Félix Houphouët-Boigny de Mathématiques et des Olympiades panafricaines de Mathématiques, Cyr Emile M`lan s`envolera pour le Canada, après un Bac C brillament obtenu au Lycée scientifique de yamoussoukro, en 1989, et une Maîtrise en mathématiques, obtenue à l`Université de Cocody en 1993. Depuis 2004, Cyr Emile M`lan, PhD, est Assistant Professor au Département de Statistiques, à University of Connecticut, Connecticut, USA.

Curriculum vitæ

EDUCATION

• 2004-Present : Assistant Professor (Department of Statistics, University of
Connecticut, Connecticut, USA).
• Oct 2002- Aug 2004 : Postdoctoral Fellow (Department of Genetic and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Canada) : Statistical Analyst of Microarray Data.
• 1997-2003 : Ph.D in statistics, (Department of Mathematics and Statistics, McGill University, Canada). Thesis Title: Bayesian Sample Size Calculations for Cohort and Case-Control Studies.
• 1994-1996 : M.Sc. in statistics, Department of Mathematics and Statistics, Université Laval, Quebec, Canada. Thesis title: Etude Comparative des Méthodes de Bradley-Terry et Saaty (``Comparative Studies of the Bradley-Terry and the Saaty Methodologies’’).
• 1989-1993 : M.Sc. in mathematics (a four year program), Department of Mathematics, Université Nationale de Cocody, Abidjan, Ivory Coast, West Africa.
• 1989 : Bac Ivoirien serie C, Yamassoukro, Ivory Coast, West Africa.

HONORS and AWARDS

• 1986: Houphouet-Boigny Mathematical Prize, level II (nationwide mathematical prize
in Ivory Coast).
• 1989: Houphouet-Boigny Mathematical Prize, level IV.
• 1989: Gold medallist at the Panafrican Mathematical Olympiad, Ibadan, Nigeria.
• 1989: Special jury price for original solutions, Ibadan, Nigeria.
• 1997-1998-1999: recipient of an ISM (Institut des Sciences Mathématiques)
scholarship, Montreal, Quebec.

EMPLOYMENT AND TEACHING EXPERIENCE

• Aug 2004 - Present: Assistant Professor (Department of Statistics, University of Connecticut, Storrs, CT, USA).
Courses Taught: STAT 220: (Statistical Methods), Fall 2004.
STAT 301 (Introduction to Applied Statistics), Fall 2005.
STAT 320 (Applied Statistics I), Fall 2006.
STAT 410 (Statistical Consulting), Spring 2005, 2006, and 2007.
STAT 100QC (Introduction to Statistics), Winter 2007,
STAT 110V (Elementary Concept of Statistics), Summer 2007.
STAT 231 (Introduction to Mathematical Statistics II), Spring 2007.
• Oct 2002-Aug 2004: Postdoctoral Fellow (Department of Genetic and Genomic Biology, Hospital for Sick Children Research Institute, Toronto, Canada). Mandate: find and/or develop statistical analysis tools for analysis of gene expression microarray data.
• Summers of 1997, 1998, 2000: Research Assistant (applied statistician) Centre for Clinical Epidemiology at the Jewish General Hospital and Community Studies, Montreal, Canada.
• May-June 1999 : Lecturer 189-203 : Principles of Statistics I, Department of Mathematics and Statistics, McGill University, Quebec, Canada.
• 1997-2001 : Teaching Assistant, Department of Mathematics and Statistics, McGill University, Montreal, Canada.
• 1994-1996 : Teaching Assistant, Department of Mathematics and Statistics, Université Laval, Quebec, Canada.

RESEARCH INTERESTS

• Microarray Data Analysis.
• Bayesian methods for sample size calculations and Bayesian optimal designs.
• Bayesian analyses of medical studies.
• Survival analysis with length-biased data.
• Vector of priorities elucidations and the methods of paired comparisons.

COMPUTER SKILLS

Good knowledge of
�� General statistic softwares: S-PLUS, R, SAS
�� Softwares for the analysis of microarray data: Bioconductor, Insightfull ArrayAnalyzer, SAM, PAM, MAANOVA, DChip, Brb-ArrayTools.
�� Sofwares on Bayesian Inferences : WinBUGS.
�� High level programming languages: Visual Fortran, C, C++.
�� Others: Maple 7, Latex, HTML.
Basic knowledge of
�� Windows, Linux, and Unix operating systems.

LANGUAGES

• French: fluent.
• English: able to read, write and speak well (2nd language).

PUBLICATIONS

• Book Chapter: Pingzhao Hu, Celia M.T. Greenwood, Cyr E. M’lan, and Joseph Beyene, Chromosal Clustering of Periodically Expressed Genes in Plasmodium falciparum, chapter 8 of “Methods of Microarray Data Analysis V”, edited by Patrick McConnell, Simon Lin, and Patrick Hurban, Springer, NY, 2007.
• Marianna O. Orlova, Konstantin B. Majorov, Irina V. Lyadova , Eugenii B. Eruslanov,
Cyr E. M`lan, Celia M.T. Greenwood, Erwin Schurr, Alexander S. Apt (2006).
Constitutive differences in gene expression profiles parallel genetic pattern of
susceptibility to tuberculosis in mice. Infection and Immunity, 74, 6, 3668-3672.
• Cyr Emile M`Lan, Lawrence Joseph, and David B. Wolfson (2006). Bayesian Sample Size Determination for Case-Control Studies. JASA - Theory and Methods, vol 101, Issue 474, 760-772.
• Susan R. Kahn, Cyr E. M’lan, Donna L. Lamping, Xavier Kurz, Anick Bedard, Lucien A. Abenhaim (2004). Relationship Between Clinical Severity of Chronic Disease and Patient-Reported Quality of Life: Results from an International Cohort Study. Journal of Vascular Surgery, 39, 4, 823-828.
• Susan R. Kahn, Cyr E. M’lan, Donna L. Lamping, Xavier Kurz, Anick Bedard, Lucien A. Abenhaim (2004). The influence of venous thromboembolism on quality of life and severity of chronic venous disease: Results from the VEINES international cohort study. Journal of Thrombosis and Haemostasis, 2: 2146-2151.
• M. Asgharian, D. B. Wolfson, and C. E. M`lan (2002). Length-biased sampling with right censoring: an unconditional approach, JASA - Theory and Methods, vol 97, Issue 457, 201-209.
• C. Wolfson, D. B. Wolfson, M. Asgharian, C. E. M`lan, T. Østbye, K. Rockwood, D. B. Hogan (2001). A Reevaluation of the Duration of Survival after the Onset of Dementia, The New England Journal of Medicine, 15, vol 334, 1111-1116.
• C. Genest and C. E. M`lan (1999). Deriving priorities from the Bradley-Terry model. Mathematical and Computer Modelling, 29, 87-102.
• Book chapter: D. B. Wolfson and C. E. M’lan, Survival Analysis, chapter 6 of ``Surgical Arithmetic: Epidemiological, Statistical and Outcome - Based Approach to Surgical Practice``, by L. Rosenberg, L. Joseph, and A. Barkun, Landes Biosciences, Austin, Texas, 2000.
SUBMITTED PAPER
• Cyr Emile M`Lan, Lawrence Joseph, and David B. Wolfson (2007). Bayesian Sample Size Determination for Binomial Proportion. Resubmitted to Bayesian Analysis.
WORKING PAPERS -- IN PROGRESS
• Cyr Emile M’lan, Celia Greenwood, Shelley Bull (2007). Estimating Global and Gene-Specific Parameters in an Unbalanced Multifactorial ANOVA model of Microarray Data.
• Cyr Emile M`Lan, Lawrence Joseph, and David B. Wolfson (2007). Bayesian Sample Size Calculations for Cohort and Case-Control when Disease Probabilities and Exposure Probabilities are Restricted.

TOPIC CONTRIBUTED AND INVITED SESSSIONS

• Organizer and Chair of Invited Session 1F on “Statistical Genetics” at ICSA 2006, Storrs, CT, USA, June 15th, 2006. Presented material on
• Organizer of Topic Contributed Session 258 on “Bayesian Sample Size and Test Presentation” at 2005 JSM, Minneapolis, MN, USA, August 9th, 2005. Presented material on “Bayesian Sample Size Calculations for Case-Control Studies”.
• Presentation at the 2005 New England Statistics Symposium, Storrs, CT, USA, April 23rd, 2005: “Normalization Technique for Microarray Data”.
• Presentation at 2004 Annual meeting of SSC, Montreal, QC, Canada, June 25th, 2004: “Detecting Differentially Expressed Genes among Human Population Subgroups”.
• Presentation at the MITACS NCE Biomedical Theme Meeting at Banff, AL, Canada, October 2003: “Detecting Differentially Expressed Genes among Human Population Subgroups”.
• Presentation at the International Biometric Society Eastern North American Region (ENAR) 2003 Spring Meeting, Tampa, FL, USA: “Bayesian Sample Size Calculations for Case-Control Studies”.
• Presentation at the Fourth International Symposium on the Analytical Hierarchy Process (ISAHP 1996), Faculty of Business Administration, Simon Fraser University, BC, Canada, July 12-15: “Priorities Derived from Pairwise Preferences via Saaty`s Method and the Bradley-Terry Model. What is the Connection?”

INVITED LECTURES
• “Bayesian Sample Size Calculation” at the UFR de mathématique et Informatique, Université Nationale de Cocody, Abidjan, Ivory Coast, West Africa, on July 13th, 2006.
• “Estimating Global and Gene-Specific Parameters in Unbalanced Multifactorial ANOVA Model of Microarray Data” at Yale University, New Haven, CT, USA, September 19th, 2005.
• “Estimating Global and Gene-Specific Parameters in Unbalanced Multifactorial ANOVA Model of Microarray Data” at Stanford University, Stanford, CA, USA, June 21st, 2005.
• “Normalization Technique for Microarray Data” at the 2005 New England Statistics Symposium, Storrs, CT, USA, April 23rd, 2005.
• “Estimating Global and Gene-Specific Parameters in Unbalanced Multifactorial ANOVA Model of Microarray Data” at Laval University, Sainte-Foy, Quebec, Canada, January 13th, 2005.
• “Estimating Global and Gene-Specific Parameters in Unbalanced Multifactorial ANOVA Model of Microarray Data” at Mount Sinaï Hospital, Toronto, ON, Canada, November 26th, 2004.
• “Estimating Global and Gene-Specific Parameters in Unbalanced Multifactorial ANOVA Model of Microarray Data” at University of Massachusetts, Amherst, MA, USA, October 20th, 2004.
• “Detecting Differentially Expressed Genes among Human Population Subgroups” at McGill University, Montreal, QC, Canada, March 25th, 2004.
• “Bayesian Sample Size Calculations for Cohort Studies” at Laval University, Quebec city, QC, Canada, October 2002.
Scholarly Reputation
Referee for the LifeTime Data Analysis journal.
Referee for the Survey Methodology journal.
Referee for the journal of Computational and Graphical Statistics.
Service and Outreach
�� Department Social Committee (Fall 2004-Present).
�� Department Library/Technical Report Committee (Fall 2006-Present)
�� Active member of the CAS/Consulting Committee, Department of Statistics (2005-Present).
�� Member of committee for International Workshop of Applied Probability (IWAP) May 14-18, 2006. Edited the abstract book which contains 188 pages.
�� Coordinate website materials with Ulysses Diva for IWAP 2006.
Other Activities
• Judge at the Tenth Annual Royal West Academy Science Fair on February 12, 1999.
• Judge at the Sixth Annual F.A.C.E. Science Fair on January 18, 1999.
• First secretary of the ``Club mathématique et informatique`` of the Lycee Scientifique de Yamoussoukro, Ivory Coast in the academic year 1988-1989.